I have two handguns with red dots: a Ruger Mark IV with a Vortex Viper and a FN FNX-45 Tactical with a Trijicon RMR. My experience with red dots on pistols is similar to Jerry's. I find i can get on target quickly, but i'm not going to win any bullseye matches with them. The 6 MOA dots aren't great for precision shooting and i find i'm a better shot with irons on other pistols. But i also have done a lot more shooting with the pistols i'm better with. I wear glasses with progressive lenses and it's definitely easier to find the dot and focus on the target than it is trying to get irons lined up in the sweet spot in the focal range of my glasses. All in all, i like shooting pistols with red dots. There's definitely a learning curve, but i'll definitely equip more pistols with red dots in the future.